Relationship of reduced cerebral blood flow and heart failure severity in elderly males
![](/themes/Miragerfos//images/openAccess.png)
2011
Аутори
Lončar, Goran![](/themes/Miragerfos/images/orcid.png)
Božić, Biljana
![](/themes/Miragerfos/images/orcid.png)
Lepić, Toplica
Dimković, Siniša
Prodanović, Nenad
Radojičić, Zoran
![](/themes/Miragerfos/images/orcid.png)
Čvorović, Vojkan
Marković, Nataša
![](/themes/Miragerfos/images/orcid.png)
Brajović, Milan
Despotović, Nebojša
Putniković, Biljana
Popović-Brkić, Vera
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Methods. aEuro integral Seventy-one CHF males with NYHA class II and III and 20 control subjects age >= a parts per thousand yen 55 years were recruited. CBF was evaluated by colour duplex sonography of extracranial arteries. Echocardiography, 6-min walk test, quality of life and endothelial function were also assessed. Serum NT-pro-BNP and adipokines levels (adiponectin and leptin) were measured. Results. aEuro integral CBF was significantly reduced in elderly patients with CHF compared to healthy controls (677 +/-+/- 170 vs 783 +/-+/- 128 ml/min, p == 0.011). Reduced CBF was associated with reduced left ventricular ejection fraction (LVEF) (r == 0.271, p == 0.022), lower 6-min walk distance (r == 0.339, p == 0.004), deteriorated quality of life (r == --0.327, p == 0.005), increased serum adiponectin (r == --0.359, p == 0.002), and NT-pro-BNP levels (r == --0.375, p == 0.001). In multivariate regression analysis, LVEF and adiponectin were independently associated with reduced CBF in C...HF patients (R LT SU2 LT /SU == 0.289). Conclusion. aEuro integral CBF was reduced in elderly males with mild-to-moderate CHF, and was associated with factors that represent the severity of CHF including high serum adiponectin and NT-pro-BNP levels, decreased LVEF, impaired physical performance, and deteriorated quality of life.
Кључне речи:
left ventricular ejection fraction / chronic heart failure / Cerebral blood flow / adiponectinИзвор:
Aging Male, 2011, 14, 1, 59-65Издавач:
- Taylor & Francis Ltd, Abingdon
DOI: 10.3109/13685538.2010.511326
ISSN: 1368-5538
PubMed: 20873985
WoS: 000286993600012
Scopus: 2-s2.0-79751514511
Институција/група
Fakultet organizacionih naukaTY - JOUR AU - Lončar, Goran AU - Božić, Biljana AU - Lepić, Toplica AU - Dimković, Siniša AU - Prodanović, Nenad AU - Radojičić, Zoran AU - Čvorović, Vojkan AU - Marković, Nataša AU - Brajović, Milan AU - Despotović, Nebojša AU - Putniković, Biljana AU - Popović-Brkić, Vera PY - 2011 UR - https://rfos.fon.bg.ac.rs/handle/123456789/737 AB - Methods. aEuro integral Seventy-one CHF males with NYHA class II and III and 20 control subjects age >= a parts per thousand yen 55 years were recruited. CBF was evaluated by colour duplex sonography of extracranial arteries. Echocardiography, 6-min walk test, quality of life and endothelial function were also assessed. Serum NT-pro-BNP and adipokines levels (adiponectin and leptin) were measured. Results. aEuro integral CBF was significantly reduced in elderly patients with CHF compared to healthy controls (677 +/-+/- 170 vs 783 +/-+/- 128 ml/min, p == 0.011). Reduced CBF was associated with reduced left ventricular ejection fraction (LVEF) (r == 0.271, p == 0.022), lower 6-min walk distance (r == 0.339, p == 0.004), deteriorated quality of life (r == --0.327, p == 0.005), increased serum adiponectin (r == --0.359, p == 0.002), and NT-pro-BNP levels (r == --0.375, p == 0.001). In multivariate regression analysis, LVEF and adiponectin were independently associated with reduced CBF in CHF patients (R LT SU2 LT /SU == 0.289). Conclusion. aEuro integral CBF was reduced in elderly males with mild-to-moderate CHF, and was associated with factors that represent the severity of CHF including high serum adiponectin and NT-pro-BNP levels, decreased LVEF, impaired physical performance, and deteriorated quality of life. PB - Taylor & Francis Ltd, Abingdon T2 - Aging Male T1 - Relationship of reduced cerebral blood flow and heart failure severity in elderly males EP - 65 IS - 1 SP - 59 VL - 14 DO - 10.3109/13685538.2010.511326 UR - conv_1306 ER -
@article{ author = "Lončar, Goran and Božić, Biljana and Lepić, Toplica and Dimković, Siniša and Prodanović, Nenad and Radojičić, Zoran and Čvorović, Vojkan and Marković, Nataša and Brajović, Milan and Despotović, Nebojša and Putniković, Biljana and Popović-Brkić, Vera", year = "2011", abstract = "Methods. aEuro integral Seventy-one CHF males with NYHA class II and III and 20 control subjects age >= a parts per thousand yen 55 years were recruited. CBF was evaluated by colour duplex sonography of extracranial arteries. Echocardiography, 6-min walk test, quality of life and endothelial function were also assessed. Serum NT-pro-BNP and adipokines levels (adiponectin and leptin) were measured. Results. aEuro integral CBF was significantly reduced in elderly patients with CHF compared to healthy controls (677 +/-+/- 170 vs 783 +/-+/- 128 ml/min, p == 0.011). Reduced CBF was associated with reduced left ventricular ejection fraction (LVEF) (r == 0.271, p == 0.022), lower 6-min walk distance (r == 0.339, p == 0.004), deteriorated quality of life (r == --0.327, p == 0.005), increased serum adiponectin (r == --0.359, p == 0.002), and NT-pro-BNP levels (r == --0.375, p == 0.001). In multivariate regression analysis, LVEF and adiponectin were independently associated with reduced CBF in CHF patients (R LT SU2 LT /SU == 0.289). Conclusion. aEuro integral CBF was reduced in elderly males with mild-to-moderate CHF, and was associated with factors that represent the severity of CHF including high serum adiponectin and NT-pro-BNP levels, decreased LVEF, impaired physical performance, and deteriorated quality of life.", publisher = "Taylor & Francis Ltd, Abingdon", journal = "Aging Male", title = "Relationship of reduced cerebral blood flow and heart failure severity in elderly males", pages = "65-59", number = "1", volume = "14", doi = "10.3109/13685538.2010.511326", url = "conv_1306" }
Lončar, G., Božić, B., Lepić, T., Dimković, S., Prodanović, N., Radojičić, Z., Čvorović, V., Marković, N., Brajović, M., Despotović, N., Putniković, B.,& Popović-Brkić, V.. (2011). Relationship of reduced cerebral blood flow and heart failure severity in elderly males. in Aging Male Taylor & Francis Ltd, Abingdon., 14(1), 59-65. https://doi.org/10.3109/13685538.2010.511326 conv_1306
Lončar G, Božić B, Lepić T, Dimković S, Prodanović N, Radojičić Z, Čvorović V, Marković N, Brajović M, Despotović N, Putniković B, Popović-Brkić V. Relationship of reduced cerebral blood flow and heart failure severity in elderly males. in Aging Male. 2011;14(1):59-65. doi:10.3109/13685538.2010.511326 conv_1306 .
Lončar, Goran, Božić, Biljana, Lepić, Toplica, Dimković, Siniša, Prodanović, Nenad, Radojičić, Zoran, Čvorović, Vojkan, Marković, Nataša, Brajović, Milan, Despotović, Nebojša, Putniković, Biljana, Popović-Brkić, Vera, "Relationship of reduced cerebral blood flow and heart failure severity in elderly males" in Aging Male, 14, no. 1 (2011):59-65, https://doi.org/10.3109/13685538.2010.511326 ., conv_1306 .